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The Solve ME/CFS Initiative (SMCI) has been the leading organization focused on myalgic encephalomyelitis (ME), commonly referred to as chronic fatigue syndrome (CFS), since being founded in 1987. SMCI envisions a world free of ME/CFS and works steadfastly to make this disease understood, diagnosable, and treatable. SMCI seeks to actively engage the entire ME/CFS community in research, works to accelerate the discovery of safe and effective treatments, and strives for an aggressive expansion of funding toward a cure.

Original Research

With a focus in three key areas (bioenergetics, immunity and inflammation, and neuroendocrine biology), SMCI is launching multiple initiatives in partnership with biotech companies, medical clinics, and universities.

BioBank and Patient Registry

SMCI’s BioBank supports the work of qualified ME/CFS researchers to accelerate progress, while our state-of-the-art Patient Registry, operated in collaboration with Dr. Susan Levine, is supported by the Robert Wood Johnson Foundation/Genetic Alliance White Label PEER Program.

Ramsay Award Program

This competitive, peer-reviewed grant program funds promising research and draws new researchers to the field.

Bioenergetics Deep Dive

Our organization is launching a multi-milliondollar,multi-year biogenetics umbrella study made up of several individually ambitious studies.

Engaging with Key Federal Agencies

SMCI is a go-to organization for the CDC and NIHregarding funding and research strategy for ME/CFS. President Carol Head, with other advocates, was recently part of meetings with the Acting Assistant Secretary of HHS.

Creating Momentum on Capitol Hill

SMCI coordinates briefings, meetings, and strategic alliances with key congressional members/staff and was a leader in the effort to reinstate the FY 2016 budget for ME/CFS research at the CDC.

Building Coalitions

SMCI partners with global organizations and advocates to bring coordinated, strategic messaging to all areas of policy.

Making ME/CFS Part of the Conversation

President Carol Head serves on the Chronic Fatigue Syndrome Advisory Committee (CFSAC), which makes recommendations to HHS and endorses or opposes legislation that may affect ME/CFS patients.

Bringing Together the Research, Advocacy, and Patient Communities

SMCI brings relevant scientific research to the community in an accessible manner, backs patient-centered research, and calls for policies and funding to improve the lives of patients.

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